You've done the research. You've read the forums at midnight. You've taken the NHS leaflets home and felt, somehow, more confused than when you started. And now you're here, wondering which supplements, if any, are actually worth your money when you're trying to conceive with a hormonal condition like PMOS (PCOS).

This is what I wish someone had told me earlier: the right supplements won't override biology, and they're not a magic fix. But they can give your body the specific nutritional support it's often chronically missing, the kind that makes a measurable difference to egg quality, ovulation regularity, and hormonal balance.

This guide walks through the full MyOva fertility range with one goal: helping you understand what each product does, why it matters, and which combination might be right for where you are right now.

What Do Fertility Supplements Actually Do for Women With PMOS (PCOS) or Other Hormonal Conditions?

Women with PMOS, endometriosis, and other hormonal conditions are commonly under-supplied in nutrients like folate, vitamin D, magnesium, and inositol. These aren't minor gaps. They connect to insulin sensitivity, inflammatory load, ovarian function, and the quality of the eggs being produced each cycle.

The research on this is actually pretty clear: supplementing strategically can shift the hormonal environment in meaningful ways. Not overnight. But over weeks and months, the cumulative effect on cycle regularity, ovulation frequency, and embryo quality can be significant, though the evidence base for individual nutrients varies in strength, and a cautious, honest reading of it matters more than a confident-sounding headline.

That said, not every product is right for every person. PMOS is wildly heterogeneous. Endometriosis creates a different set of needs. Stress and nervous system dysregulation need a different kind of support altogether. So let's break it down properly.

The Full MyOva Fertility Range: What's in Each Product and Why It Matters

Myoplus: The All-Rounder for PMOS (PCOS) Symptom Support

Myoplus contains myo-inositol, vitamin B6, folate, and chromium, a targeted formula for women managing PMOS who want broad hormonal support alongside fertility benefits.

Myo-inositol is the ingredient that gets most of the attention in PCOS fertility research, and for good reason. It belongs to the vitamin B family and plays a role in insulin signalling. Insulin resistance is present in a substantial proportion of PMOS cases, estimates in the research range from roughly 35% to 80% of women, depending on body weight, ethnicity, and how it's measured, and it occurs whether or not weight is a factor.¹ Correcting insulin dysregulation often has a downstream effect on androgens, LH levels, and ovulation frequency.

A 2024 systematic review and meta-analysis, commissioned to inform the international evidence-based PCOS guidelines, examined the research on inositol supplementation in PCOS. Its conclusion is honest rather than hyped: the evidence for myo-inositol specifically is described as limited and inconclusive on some outcomes, with more consistent signals for D-chiro-inositol's role in ovulation, and no meaningful difference found compared with metformin in several trials.² That's not a reason to dismiss myo-inositol. It's a reason to hold the claims about it to an honest standard, which is exactly what this guide tries to do.

The vitamin B6 in Myoplus contributes to the regulation of hormonal activity, an authorised claim under EU and UK nutrition law. The folate is provided as calcium L-methylfolate, a form that's directly usable by the body. Chromium rounds out the formula, contributing to the maintenance of normal blood glucose levels, useful for anyone navigating the blood sugar irregularities that often sit at the root of PMOS-related hormonal chaos.

Myoplus is vegan and vegetarian-friendly, convenient to take, and provides a full 30-day supply per bottle at the standard dose. It's typically the starting point for women who are newer to PMOS supplement support or want a clean, focused option.

PMOS (PCOS) Symptom Support

MyOva Myoplus

4000mg myo-inositol daily alongside vitamin B6, folate, and chromium. The UK's original myo-inositol formula, in an easy-to-take chewable or crushable tablet.

£32.00

Shop Myoplus →

MyOva Preconception: The Comprehensive Fertility Formula

MyOva Preconception is an all-in-one formula designed to cover multiple nutritional bases for egg quality, hormonal balance, and reproductive health in the months before conception.

If Myoplus is the starting point, Preconception is the fuller picture.

This supplement was formulated for the preconception window, broadly the three to six months before you try to conceive, when the eggs you'll eventually use are maturing. Egg maturation (oogenesis) takes roughly 90 days. What you put into your body today plays a role in shaping the eggs that will matter in three months. That's not alarmist. It's just biology.

→ Shop the MyOva Preconception Supplement

The Preconception formula contains:

• Myo-inositol (2000mg daily), for insulin sensitivity and ovarian function support
• Folate (5-MTHF), the bioavailable methylated form, which contributes to maternal tissue growth during pregnancy
• Vitamin D3, relevant because vitamin D receptors are present in ovarian tissue and the endometrium³
• Coenzyme Q10 (as Ubiquinol), a mitochondrial antioxidant studied for its role in egg quality, particularly for women over 35 or those with diminished ovarian reserve
• N-Acetyl Cysteine (NAC), supports glutathione production and has clinical evidence for a role in ovulation induction in PCOS when used alongside clomiphene citrate⁴
• Alpha Lipoic Acid, an antioxidant that supports mitochondrial function and insulin sensitivity
• L-Arginine, an amino acid involved in blood flow, relevant to endometrial receptivity
• Zinc, contributes to normal fertility and reproduction, and to normal DNA synthesis
• Selenium, supports thyroid function (often disrupted in hormonal conditions)
• Magnesium, involved in hundreds of enzymatic reactions, including those governing insulin signalling
• Iron, low iron is associated with anovulation; the Preconception formula uses ferrous fumarate
• Iodine, essential for thyroid hormone synthesis, which regulates menstrual cycle function
• Chromium, for glucose regulation and insulin sensitivity
• Full B-vitamin complex, B1, B2, B3, B6, B12, Biotin, and Pantothenic Acid, supporting energy metabolism and nervous system function
• Vitamins C and E, antioxidant support
• Beta-carotene, a precursor to vitamin A
• Copper, balances zinc and supports iron metabolism

That's a genuinely broad formula. Not because more ingredients automatically means better, but because fertility support in women with hormonal conditions is rarely a single-nutrient problem. The Preconception supplement was built to reflect that, with each component chosen for a clear, defensible reason rather than to chase a trending ingredient list.

→ Shop the MyOva Preconception Supplement

Comprehensive Preconception Support

MyOva Preconception

2000mg myo-inositol alongside 16 vitamins and minerals, including folate, vitamin D3, zinc, NAC, alpha lipoic acid, and CoQ10 (ubiquinol). Formulated for the months before conception.

£36.00

Shop Preconception →

MyOva Fertility Support Botanical Tea: The Daily Ritual for Stress Resilience

The MyOva Fertility Support Botanical Tea is a loose-leaf herbal blend designed as a daily ritual to support hormonal balance, emotional wellbeing, and stress resilience, intended for consistent use across roughly three cycles.

Not everything about preparing for pregnancy is nutritional. Some of it is nervous system. Some of it is cortisol. Some of it is simply the emotional weight of a chapter that asks a great deal of you.

The Fertility Support Tea was created with that in mind, as something that works alongside your supplement routine rather than replacing it.

→ Shop the MyOva Fertility Support Botanical Tea

Here's what's inside and why each ingredient earns its place:

• Shatavari root (Asparagus racemosus): one of Ayurveda's most-used female tonic herbs, traditionally used to support the reproductive system and hormonal balance.⁵
• Ashwagandha root (Withania somnifera): an adaptogen studied in a randomised controlled trial that found it significantly reduced serum cortisol and self-reported stress scores compared with placebo.⁶ This matters for fertility: chronically elevated cortisol suppresses GnRH release from the hypothalamus, which in turn blunts LH and FSH signalling, the hormones that drive ovulation.
• Lemon balm leaf (Melissa officinalis): traditionally used to support relaxation and emotional calm.
• Milk thistle seed (Silybum marianum): traditionally used to support liver health. The liver is responsible for clearing excess oestrogen, so supporting liver function is a reasonable foundation for hormonal balance.
• Lady's mantle herb (Alchemilla vulgaris): a longstanding botanical in women's herbal traditions, historically used to support menstrual health.
• Rose petals (Rosa gallica): traditionally used to support emotional wellbeing, and adds a soothing finish to the blend.
• Cacao husks and nibs (Theobroma cacao): adds warmth and depth to the blend.
• Vitamin B6: contributes to the regulation of hormonal activity, normal psychological function, and the reduction of tiredness and fatigue, all EU-authorised health claims.
• Zinc citrate: contributes to normal fertility and reproduction.
• Chromium picolinate: contributes to the maintenance of normal blood glucose levels.

The tea is designed to be taken consistently over roughly three cycles, because rituals that compound are what create change. One cup won't shift your cortisol. Ninety days of consistent daily intention has a far better shot.

It's vegan, free from unnecessary fillers, and made with loose-leaf botanicals. As Leila puts it: preparing for conception isn't about rushing your body, it's about honouring it.

→ Shop the MyOva Fertility Support Botanical Tea

Daily Ritual for Stress Resilience

MyOva Fertility Support Herbal Tea

Shatavari and ashwagandha alongside zinc, vitamin B6, and chromium. A loose-leaf daily ritual designed for consistent use across your preconception cycles.

£24.00

Shop the Tea →

Which MyOva Product Is Right for You?

Can you take Myoplus and Preconception together? Yes. For a higher daily myo-inositol intake, two Myoplus tablets can be combined with the Preconception dose, giving 4000mg of myo-inositol daily in total. Preconception already contains 2000mg of myo-inositol plus folate and chromium, so combining isn't strictly necessary; if you're ready for the fuller formula, that's the one to lean into.

Can you take the Fertility Tea alongside Preconception? Yes, they're designed to complement each other, with no overlapping ingredients that raise a concern. As always, if you're on prescribed medication, check with your GP before adding anything new.

When Should You Start Taking Fertility Supplements?

Your body is not imagining it: the "start earlier than you think" advice is genuinely grounded in the biology of oogenesis.

That said, if you're already trying, starting now is still meaningful. Egg quality isn't fixed. Mitochondrial function and oxidative stress levels can respond to nutritional intervention over time. You're not too late.

What you can't do is take supplements for two weeks and expect to see a difference. A more honest timeline looks like this:

• Weeks 4-8: energy, cycle regularity, and skin may begin to shift
• Months 2-3: ovulation pattern and hormonal markers are more likely to show measurable change
• Months 3-6: egg quality improvements, the longer-arc benefit, become more relevant

This is also why the Fertility Support Tea is designed for roughly three-cycle use. Consistent daily rituals over 90 days compound. That's the whole principle.

Consistency matters more than perfection. Taking your supplements and your cup of tea at the same time each day, with food, is enough.

How Does Myo-Inositol Support Fertility Specifically?

This is what I wish someone had explained earlier, because "myo-inositol helps fertility" is a headline that doesn't actually tell you why.

Here's the proposed mechanism: in PMOS, cells become resistant to insulin. To compensate, the body produces more insulin. Excess insulin stimulates the ovaries to produce more androgens (testosterone and related hormones). Elevated androgens disrupt follicle development and interfere with normal LH signalling, which is what triggers ovulation.

Myo-inositol is thought to act as a second messenger in insulin signalling, and supplementing it is proposed to help restore insulin sensitivity, which in turn may reduce androgen production and support more normal hypothalamic-pituitary-ovarian axis function.

The honest picture, per the most recent systematic review commissioned for the international PCOS guidelines, is more mixed than the supplement industry often presents: evidence for D-chiro-inositol shows a more consistent signal for ovulation specifically, while myo-inositol's own evidence base is still described as limited and inconclusive on several outcomes.² A separate meta-analysis of six randomised trials in women undergoing ICSI or IVF-ET (913 patients in total) found inositol supplementation was associated with a higher clinical pregnancy rate (33.3% versus 27.6% in controls) and a lower miscarriage rate (5.9% versus 17.6%), a genuinely encouraging result, though it's one meta-analysis of a specific patient group rather than a universal guarantee.⁷

What that means practically: myo-inositol is a reasonable, evidence-informed choice, not a guaranteed fix. Setting your expectations at "supports the underlying biology" rather than "solves PMOS" is the more accurate framing, and the one this guide is built around.

Does CoQ10 Actually Improve Egg Quality?

Your eggs require more mitochondrial energy than almost any other cell in the body. When mitochondrial function declines, which happens with age, oxidative stress, and in certain hormonal conditions, egg quality can suffer.

CoQ10, specifically in its reduced form ubiquinol (the form used in the Preconception formula), supports the mitochondrial electron transport chain. It functions both as an energy cofactor and as a lipid-soluble antioxidant that helps protect egg cells from oxidative damage during maturation.

A widely cited animal study from a Toronto research group found that CoQ10 supplementation reversed age-related declines in egg quality in mice, an important mechanistic finding, though it's mouse data and doesn't translate directly to human dosing or outcomes.⁸ In humans, a 2018 randomised controlled trial in low-prognosis young women with decreased ovarian reserve undergoing IVF found that CoQ10 pretreatment significantly improved ovarian response and embryo quality compared with placebo.⁹

For women over 35, or those diagnosed with diminished ovarian reserve specifically, CoQ10 is one of the more evidence-supported additions to a preconception protocol, though it's worth being clear that this is the population the strongest human data actually covers.

What Role Does Vitamin D Play in Female Fertility?

Vitamin D isn't just a bone health nutrient. Vitamin D receptors are expressed throughout the female reproductive system, in the ovaries, endometrium, and fallopian tubes. The body expects vitamin D to be present in reproductive tissue.

In PMOS specifically, vitamin D deficiency is common, and low vitamin D has been associated with worsening insulin resistance and higher androgen levels in observational research, though observational data can't prove that correcting vitamin D levels alone reverses those changes.³

In the UK, government data estimates that around 18% to 24% of adults aged 19 to 64 have deficient vitamin D status (blood levels below 25nmol/L) year-round, a figure that rises substantially in winter, to roughly 30% to 40%, when sunlight exposure drops.¹⁰ That makes supplementation, particularly through autumn and winter, a reasonable baseline for most people in the UK rather than a niche recommendation.

Does Stress Actually Affect Fertility?

Cortisol is the body's primary stress hormone. When chronically elevated, it can suppress gonadotropin-releasing hormone (GnRH) release from the hypothalamus. GnRH is the signal that tells the pituitary to release LH and FSH, the hormones that drive follicle development and ovulation.

In plain terms: prolonged stress signals to the brain that this isn't a safe time to reproduce, and the ovarian axis can slow in response.

This is why ashwagandha, a key ingredient in the Fertility Support Tea, has genuine relevance in a preconception context. A randomised controlled trial found that a high-concentration ashwagandha root extract significantly reduced serum cortisol and self-reported stress scores compared with placebo.⁶

Lemon balm, also in the tea, is traditionally used for its calming and sleep-supporting properties, both of which interact with the stress-cortisol cycle.

Supplements address what you eat. The tea addresses how your nervous system is running. Both matter.

The Most Important Thing to Know

Supplements and herbal teas are nutritional and botanical support, and meaningfully good support, at that. But they work best as part of a wider approach that includes understanding your cycle, managing stress where possible, and working with healthcare professionals who take your concerns seriously.

If you've felt dismissed by a GP, been told your symptoms are "normal," or left a consultation with more questions than answers, you're not alone. Your instinct to look further is valid. Hormonal literacy isn't complicated. It's just rarely taught.

The research supports targeted, honestly-framed supplementation. Your body can respond. Give it what it's often missing, give it time, and pay attention to the signals it gives back.

Frequently Asked Questions

Can I take MyOva supplements alongside my prescribed medication?

If you're taking any prescribed medications, including metformin, hormonal contraceptives while cycling off, or fertility drugs, check with your GP or consultant before adding supplements or herbal teas.

How long do I need to take fertility supplements before trying to conceive?

The recommended starting point is three to six months before you plan to try, to work within the roughly 90-day egg maturation window. Starting at any point is better than not starting. If you're already trying, begin now and give it three months minimum to assess impact.

Is Preconception suitable if I have endometriosis rather than PMOS?

Yes, the Preconception supplement suits women with endometriosis, given its antioxidant-forward formula (NAC, CoQ10, Alpha Lipoic Acid, vitamins C and E). The Fertility Support Tea's milk thistle and ashwagandha are also relevant for inflammatory load and stress resilience.

Do I need a separate folic acid supplement if I'm taking Preconception?

No. Preconception contains folate as 5-MTHF, the bioavailable methylated form. You don't need to add a separate supplement on top. If you've been advised to take a higher dose, check the label and discuss it with your doctor.

Are MyOva fertility products vegan-friendly?

Myoplus and the Fertility Support Botanical Tea are both suitable for vegans and vegetarians. Please check the Preconception product page for the most current allergen and dietary information, as formulas can be updated.

Related Blogs

• What Is Myo-Inositol and How Does It Help PMOS (PCOS)?
• Irregular Periods and PMOS (PCOS): 5 Ways to Regulate Your Cycle
• What Blood Tests Should I Ask For With PMOS (PCOS)? The Complete Guide

References

1. Prosperi S, Chiarelli F. Insulin resistance, metabolic syndrome and polycystic ovaries: an intriguing conundrum. Front Endocrinol. 2025;16:1669716.
2. Fitz VW, Graca S, Mahalingaiah S, et al. Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines. J Clin Endocrinol Metab. 2024;109(6):1630-1655. doi:10.1210/clinem/dgad762
3. Lerchbaum E, Obermayer-Pietsch B. Vitamin D and fertility: a systematic review. Eur J Endocrinol. 2012;166(5):765-778.
4. Salehpour S, et al. N-acetyl-cysteine as an adjuvant to clomiphene citrate for successful induction of ovulation in infertile patients with polycystic ovary syndrome. J Obstet Gynaecol Res. 2012;38(9):1182-1186.
5. Pandey AK, et al. Shatavari (Asparagus racemosus Wild): a review on its cultivation, morphology, phytochemistry and pharmacological importance. Int J Pharm Sci Res. 2018;9(8):3214-3226.
6. Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012;34(3):255-262.
7. Zheng X, Lin D, Zhang Y, Lin Y, Song J, Li S, Sun Y. Inositol supplement improves clinical pregnancy rate in infertile women undergoing ovulation induction for ICSI or IVF-ET. Medicine (Baltimore). 2017;96(49):e8842.
8. Ben-Meir A, et al. Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging. Aging Cell. 2015;14(5):887-895.
9. Xu Y, et al. Pretreatment with coenzyme Q10 improves ovarian response and embryo quality in low-prognosis young women with decreased ovarian reserve: a randomized controlled trial. Reprod Biol Endocrinol. 2018;16(1):29.
10. Scientific Advisory Committee on Nutrition (SACN). Vitamin D and Health. Public Health England; 2016.

Leila Martyn

Leila is the founder of MyOva, a women's wellness brand specialising in natural hormonal health and PCOS support. Drawing on lived experience and scientific research, Leila shares trusted, evidence-based guidance to help women understand their hormones, support cycle balance, and feel informed in their health journey.

This article is for educational purposes only and does not constitute medical advice. Food supplements should not be used as a substitute for a varied and balanced diet. Please consult your GP, gynaecologist, or fertility specialist before starting any new supplement or herbal product, particularly if you are undergoing fertility treatment, pregnant, breastfeeding, or taking prescribed medication.

References