You've done the research. You've read the forums at midnight. You've taken the NHS leaflets home and felt, somehow, more confused than when you started. And now you're here, wondering which supplements, if any, are actually worth your money when you're trying to conceive with a hormonal condition like PCOS.

Here's what I wish someone had told me earlier: the right supplements won't override biology, and they're not a magic fix. But they can give your body the specific nutritional support it's often chronically missing — the kind that makes a measurable difference to egg quality, ovulation regularity, and hormonal balance.

This guide walks through the full MyOva fertility range with one goal: helping you understand what each product does, why it matters, and which combination might be right for where you are right now.

Fertility supplements work by correcting nutritional deficiencies and supporting the hormonal pathways that regulate ovulation, egg quality, and uterine health — not by forcing the body to do something it can't.

Women with PCOS, endometriosis, and other hormonal conditions are disproportionately deficient in nutrients like folate, vitamin D, magnesium, and inositol. These aren't minor gaps. They directly affect insulin sensitivity, inflammatory load, ovarian function, and the quality of the eggs being produced each cycle [Unfer et al., 2017; Holton et al., 2019].

The research on this is actually pretty clear: supplementing strategically can shift the hormonal environment in meaningful ways. Not overnight. But over weeks and months, the cumulative effect on cycle regularity, ovulation frequency, and embryo quality can be significant.

That said — not every product is right for every person. PCOS is wildly heterogeneous. Endometriosis creates a different set of needs. Stress and nervous system dysregulation need a different kind of support altogether. So let's break it down properly.

Myo-Plus contains myo-inositol, folate, and chromium — a targeted trio for women managing PCOS who want broad hormonal support alongside fertility benefits.

Myo-inositol is the ingredient that gets most of the attention in PCOS fertility research — and for good reason. It belongs to the B-vitamin family and plays a central role in insulin signalling. In women with PCOS, insulin resistance is thought to be present in up to 70% of cases, whether or not weight is a factor [Azziz et al., 2016]. Correcting insulin dysregulation often has a downstream effect on androgens, LH levels, and ovulation frequency.

A 2018 meta-analysis published in Endocrine Connections found that myo-inositol supplementation significantly improved oocyte quality, clinical pregnancy rates, and ovulation in women with PCOS undergoing assisted reproduction [Zheng et al., 2018]. Even for women trying naturally, the evidence for improved cycle regularity and reduced androgen levels is compelling.

The folate in Myo-Plus matters too — and it's the methylated form (5-MTHF), which is directly usable by the body regardless of MTHFR gene variants. Around 40% of the population carries a variant that reduces their ability to convert standard folic acid, making this distinction more important than most people realise [Greenberg et al., 2011].

Chromium rounds out the formula by supporting healthy blood glucose metabolism — useful for anyone navigating the blood sugar irregularities that often sit at the root of PCOS-related hormonal chaos.

Myo-Plus is vegan and vegetarian-friendly, convenient to take, and provides a full 30-day supply per bottle. It's typically the starting point for women who are newer to PCOS supplement support or want a clean, focused option.

The MyOva Preconception supplement is an award-winning all-in-one formula designed to cover every key nutritional base for egg quality, hormonal balance, and reproductive health in the months before conception.

If Myo-Plus is the starting point, Preconception is the full picture.

This supplement was formulated specifically for the preconception window — the three to six months before you try to conceive — when the quality of the eggs you'll be using is being determined right now. Egg maturation (oogenesis) takes roughly 90 days. What you put into your body today is, quite literally, shaping the eggs that will matter in three months. That's not alarmist. It's just biology.

→ Shop the MyOva Preconception Supplement

The Preconception formula contains:

• Myo-inositol — for insulin sensitivity and ovarian function (as above)
• Folate (5-MTHF) — the bioavailable form essential for neural tube development and DNA synthesis
• Vitamin D3 — deficiency is strongly associated with reduced fertility outcomes; vitamin D receptors are present in ovarian tissue and the endometrium [Lerchbaum & Obermayer-Pietsch, 2012]
• Coenzyme Q10 (as Ubiquinol) — a mitochondrial antioxidant shown to improve egg quality, particularly relevant for women over 35 or those with diminished ovarian reserve [Ben-Meir et al., 2015]
• N-Acetyl Cysteine (NAC) — supports glutathione production (your body's master antioxidant), reduces inflammation, and has shown clinical benefit for ovulation induction in PCOS [Salehpour et al., 2012]
• Alpha Lipoic Acid — another powerful antioxidant that supports mitochondrial function and insulin sensitivity
• L-Arginine — an amino acid that supports blood flow to the uterus and ovaries, which matters for endometrial receptivity
• Zinc — critical for follicle development, progesterone production, and DNA repair in developing eggs
• Selenium — supports thyroid function (often disrupted in hormonal conditions) and protects eggs from oxidative damage
• Magnesium — involved in over 300 enzymatic reactions, including those governing insulin signalling and progesterone activity
• Iron — low iron is associated with anovulation; the Preconception formula uses a well-tolerated form
• Iodine — essential for thyroid hormone synthesis, which directly regulates menstrual cycle function
• Chromium — for glucose regulation and insulin sensitivity
• Full B-vitamin complex — B1 (Thiamine), B2 (Riboflavin), B3 (Niacin), B6, B12, Biotin, and Pantothenic Acid — supporting energy metabolism, hormone synthesis, and nervous system function
• Vitamins C and E — antioxidant protection against oxidative stress in reproductive tissue
• Beta-carotene — a precursor to vitamin A that supports endometrial health and immune function
• Copper — balances zinc and supports iron metabolism

That's a genuinely comprehensive formula. Not because more ingredients automatically means better — but because fertility in women with hormonal conditions is rarely a single-nutrient problem. It's systemic. The Preconception supplement was built to reflect that.

Each component has a clear mechanistic rationale and, in most cases, clinical evidence behind it. This isn't a case of throwing every trending ingredient at the wall. It's a formula built with intention.

→ Shop the MyOva Preconception Supplement

The MyOva Fertility Support Botanical Tea is a premium loose-leaf herbal blend designed as a calming daily ritual to support hormonal balance, emotional wellbeing, and stress resilience — designed for consistent use across three preconception cycles.

Not everything about preparing for pregnancy is nutritional. Some of it is nervous system. Some of it is cortisol. Some of it is simply the emotional weight of a chapter that asks a great deal of you.

The Fertility Support Tea was created with that in mind — as something that works alongside your supplement protocol. A moment of intentional care that, practised daily over time, adds up to something meaningful.

→ Shop the MyOva Fertility Support Botanical Tea

Here's what's inside and why each ingredient earns its place:

• Shatavari root (Asparagus racemosus) — one of Ayurveda's most respected female tonic herbs, traditionally used to support the reproductive system and hormonal balance. Emerging research points to adaptogenic properties with relevance to ovarian function [Pandey et al., 2018].
• Ashwagandha root (Withania somnifera) — a clinically studied adaptogen shown to reduce cortisol levels in randomised controlled trials [Chandrasekhar et al., 2012]. This matters for fertility: elevated cortisol suppresses GnRH release from the hypothalamus, which in turn blunts LH and FSH signalling — the very hormones that drive ovulation. Managing stress load during the preconception period is physiologically relevant, not just a wellness nice-to-have.
• Lemon balm leaf (Melissa officinalis) — traditionally used to support relaxation and emotional calm; studied for anxiolytic and sleep-supporting properties, both of which interact with the stress-cortisol cycle.
• Milk thistle seed (Silybum marianum) — traditionally used to support liver health. The liver is responsible for metabolising and clearing excess oestrogen; supporting liver function is a foundational step for healthy hormonal balance.
• Lady's mantle herb (Alchemilla vulgaris) — a longstanding botanical in women's herbal traditions, historically used to support menstrual health and cycle regularity.
• Rose petals (Rosa gallica) — traditionally used to support emotional wellbeing; adds a soothing finish to the blend.
• Cacao husks and nibs (Theobroma cacao) — adds warmth and depth; cacao naturally contains magnesium and theobromine.
• Vitamin B6 (Pyridoxine hydrochloride) — contributes to the regulation of hormonal activity, normal psychological function, and the reduction of tiredness and fatigue. These are EU-authorised health claims.
• Zinc citrate — contributes to normal fertility and reproduction. Zinc is essential for follicle development, progesterone synthesis, and DNA integrity in developing eggs.
• Chromium picolinate — contributes to maintenance of normal blood glucose levels, supporting the insulin balance that underpins healthy ovulation.

The tea is designed to be taken consistently over three cycles — because rituals that compound are what create change. One cup won't shift your cortisol. Ninety days of consistent daily intention has a far better shot.

It's vegan, free from unnecessary fillers, and made with premium loose-leaf botanicals. As Leila puts it: preparing for conception isn't about rushing your body — it's about honouring it.

→ Shop the MyOva Fertility Support Botanical Tea

Start with Myo-Plus. It's the most focused entry point — particularly if insulin resistance, irregular cycles, or androgen-related symptoms (acne, hair thinning) are your primary concerns. Getting your blood sugar and inositol levels in a better place creates the hormonal foundation everything else builds on.

Preconception is where to focus. The breadth of the formula means you're covering egg quality, ovulation support, endometrial health, and the micronutrient gaps that PCOS creates — all in one product. The 90-day egg maturation cycle makes starting early genuinely worth it.

Preconception is the stronger choice. Conditions involving inflammation, immune dysregulation, or hormonal fluctuation benefit from the antioxidant and anti-inflammatory ingredients in this formula — CoQ10, NAC, Alpha Lipoic Acid, vitamins C and E — alongside the hormonal support nutrients.

Add the Fertility Support Botanical Tea to your daily routine. The cortisol-fertility connection is real — elevated stress hormones actively suppress the ovulation signalling cascade. Ashwagandha and lemon balm in the tea address the nervous system dimension that no capsule supplement is designed to target.

The tea pairs seamlessly alongside Preconception for women who want to cover both the nutritional and the nervous-system dimensions of preconception support. It also works well as a standalone option for women who prefer a food-first or ritual-led approach.

Yes. For higher daily myo-inositol intake, you can combine 2 tablets of Myoplus with the daily dose of Preconception.This provides 4000mg of myo-inositol daily (e.g., 1 tablet of Myoplus + 2 tablets of the second supplement in the morning, and the same in the evening). The Preconception however already contains 2000mg of myo-inositol, plus folate, and chromium, so taking both simultaneously isn't strictly necessary. If you're ready for the full preconception formula, that's the one to lean into.

Yes — they're designed to complement each other. The tea and the Preconception supplement have different mechanisms and no overlapping ingredients that would cause concern. As always, if you're on prescribed medication, check with your GP before adding anything new.

Ideally, start taking fertility supplements three to six months before you plan to try to conceive, as egg quality is determined during the 90-day maturation cycle that precedes ovulation.

Your body is not imagining it. The "start earlier than you think" advice is genuinely evidence-based here.

That said — if you're already trying, starting now is still meaningful. Egg quality isn't fixed. Mitochondrial function and oxidative stress levels respond to nutritional intervention over time. You're not too late.

What you can't do is take supplements for two weeks and expect to see a difference. The honest timeline is:

• Weeks 4–8: Energy, cycle regularity, and skin may begin to shift
• Months 2–3: Ovulation pattern and hormonal markers more likely to show measurable change
• Months 3–6: Egg quality improvements — the longer-arc benefit — become more relevant

This is also why the Fertility Support Tea is specifically designed for three-cycle use. Consistent daily rituals over 90 days compound. That's the whole principle.

Consistency matters far more than perfection. Taking your supplements and your cup of tea at the same time each day, with food, is enough.

Myo-inositol improves insulin sensitivity in women with PCOS, which reduces elevated androgens and LH, restores ovulation, and improves egg quality — all key fertility factors.

This is what I wish someone had explained earlier, because "myo-inositol helps fertility" is a headline that doesn't actually tell you why.

Here's the mechanism: in PCOS, cells become resistant to insulin. To compensate, the body produces more insulin. Excess insulin stimulates the ovaries to produce more androgens (testosterone and related hormones). Elevated androgens disrupt follicle development and interfere with normal LH signalling, which is what triggers ovulation.

Myo-inositol acts as a second messenger in insulin signalling. Supplementing it helps restore normal insulin sensitivity — which reduces androgen production — which allows the hypothalamic-pituitary-ovarian axis to function more normally — which means more regular ovulation [Nestler et al., 1999; Unfer et al., 2017].

This isn't theoretical. A clinical trial published in Gynecological Endocrinology found that myo-inositol supplementation for six months in anovulatory women with PCOS resulted in a 69% ovulation rate, compared to 52% in the control group [Papaleo et al., 2007].

The research on egg quality in IVF settings is also strong — multiple trials have shown improved oocyte quality and fertilisation rates in women taking myo-inositol prior to egg collection.

CoQ10 (as ubiquinol) supports mitochondrial energy production in egg cells, which declines with age and oxidative stress — supplementing it has shown measurable improvement in egg quality in clinical trials.

Your eggs require more mitochondrial energy than almost any other cell in the body. When mitochondrial function declines — which happens with age, oxidative stress, and in certain hormonal conditions — egg quality suffers.

CoQ10, specifically in its reduced form ubiquinol (which is what's in the Preconception formula), supports the mitochondrial electron transport chain. It's both an energy cofactor and a lipid-soluble antioxidant that protects egg cells from oxidative damage during maturation.

A landmark animal study from Toronto demonstrated that CoQ10 supplementation reversed age-related declines in egg quality in mice [Ben-Meir et al., 2015]. Human clinical data is still building, but a 2018 trial found that CoQ10 supplementation in poor-responder IVF patients significantly improved ovarian response and embryo quality compared to placebo [Xu et al., 2018].

For women over 35, or those diagnosed with diminished ovarian reserve, CoQ10 is one of the most evidence-supported additions you can make to a preconception protocol.

Vitamin D deficiency is associated with lower pregnancy rates, reduced ovarian reserve, and poorer IVF outcomes — supplementing vitamin D3 to adequate levels supports both ovarian function and endometrial receptivity.

Vitamin D isn't just a bone health nutrient. Vitamin D receptors are expressed throughout the female reproductive system — in the ovaries, endometrium, and fallopian tubes. The body expects vitamin D to be present in reproductive tissue.

In PCOS specifically, vitamin D deficiency is disproportionately common, and low vitamin D is correlated with worsening insulin resistance, higher androgen levels, and reduced AMH response [Lerchbaum & Obermayer-Pietsch, 2012].

In the UK, vitamin D deficiency is estimated to affect over 40% of the population — making supplementation less a "nice to have" and more of a reasonable baseline, especially through autumn and winter [SACN, 2016].

Elevated cortisol suppresses the hormonal signals that trigger ovulation — managing stress load is a physiologically relevant part of preconception support, not just a wellness platitude.

Cortisol is the body's primary stress hormone. When chronically elevated, it suppresses gonadotropin-releasing hormone (GnRH) from the hypothalamus. GnRH is the signal that tells your pituitary to release LH and FSH — the hormones that drive follicle development and ovulation.

In plain terms: prolonged stress tells the brain this isn't a safe time to reproduce. The ovarian axis slows in response.

This is why ashwagandha — a key ingredient in the Fertility Support Tea — has genuine clinical relevance in a preconception context. A randomised controlled trial published in the Indian Journal of Psychological Medicine found that ashwagandha root extract significantly reduced serum cortisol and self-reported stress scores compared to placebo [Chandrasekhar et al., 2012].

Lemon balm, also in the tea, has been studied for its anxiolytic and sleep-supporting properties — both of which interact with the stress-cortisol cycle.

Supplements address what you eat. The tea addresses how your nervous system is running. Both matter.

If you're taking any prescribed medications — including metformin, hormonal contraceptives (while cycling off), or fertility drugs — check with your GP or consultant before adding supplements or herbal teas. The MyOva team is also available to help with questions about specific combinations.

The recommended starting point is three to six months before you plan to try, to capture the 90-day egg maturation window. Starting at any point is better than not starting. If you're already trying, begin now and give it three months minimum to assess impact.

Yes — the Preconception supplement is well-suited to women with endometriosis, given its antioxidant-heavy formula (NAC, CoQ10, Alpha Lipoic Acid, vitamins C and E). The Fertility Support Tea's milk thistle and ashwagandha are also relevant for inflammatory load and stress resilience. If you're managing endometriosis alongside fertility concerns, the combination of Preconception and the tea covers a lot of relevant ground.

Yes — they're complementary, not overlapping. The tea covers the botanical, adaptogenic, and emotional-support dimension; the Preconception supplement covers the nutritional and micronutrient dimension. Many women in the preconception window choose both for whole-picture support.

No — the Preconception supplement contains 400mcg of folate as 5-MTHF, the bioavailable methylated form. You don't need to add a separate supplement on top. If you've been advised to take a higher dose (800mcg+), check the label and discuss with your doctor.

Myo-Plus and the Fertility Support Botanical Tea are both suitable for vegans and vegetarians. Please check the Preconception product page for the most current allergen and dietary information, as formulas can be updated.

Your diagnosis is a starting point, not a verdict.

Supplements and herbal teas are nutritional and botanical support — and meaningfully good support, at that. But they work best as part of a wider approach that includes understanding your cycle, managing stress where possible, and working with healthcare professionals who take your concerns seriously.

If you've felt dismissed by a GP, been told your symptoms are "normal," or left a consultation with more questions than answers — you're not alone. Your instinct to look further is valid. Hormonal literacy isn't complicated. It's just rarely taught.

The research supports targeted supplementation. Your body can respond. Give it what it's often missing, give it time, and pay attention to the signals it gives back.

→ Shop the MyOva Preconception Supplement

→ Shop the MyOva Fertility Support Botanical Tea

• What Is Myo-Inositol and How Does It Help PCOS?
• PCOS and Ovulation: Why Your Cycle Might Be Irregular and What to Do About It
• The PCOS Diet Guide: What to Eat to Support Hormonal Balance
• Understanding Your Hormonal Blood Tests: A Plain-English Guide
• PCOS and Egg Quality: What You Can Actually Do About It

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10. Salehpour, S. et al. (2012). N-acetyl-cysteine as an adjuvant to clomiphene citrate for successful induction of ovulation in infertile patients with polycystic ovary syndrome. Journal of Obstetrics and Gynaecology Research, 38(9), 1182–1186.
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This article is for educational purposes only and does not constitute medical advice. Please consult your GP, gynaecologist, or fertility specialist before starting any new supplement or herbal product, particularly if you are under fertility treatment, pregnant, breastfeeding, or taking prescribed medication.